Table 1. Abbreviations used to designate substrate specificities of TyrA homologs

AroPath Project

Table 1. Abbreviations used to designate substrate specificities of tyrA/TyrA homologs

Abbreviation^a		Description of specificity^b
Gene	Gene Product	Description of specificity^b
tyrA_x	TyrA_x	Specificity for cyclohexadienyl substrate is unknown
tyrA_c	TyrA_c	Broad-specificity cyclohexadienyl dehydrogenase (CDH)
tyrA_p	TyrA_p	Narrow-specificity prephenate dehydrogenase (PDH)
tyrA_{c_Δ}	TyrA_{c_Δ}	Broad-specificity cyclohexadienyl dehydrogenase having catalytic-core indels in correlation with an extra-core extension
tyrA_a	TyrA_a	Narrow-specificity arogenate dehydrogenase (ADH)

_NADtyrA_a	_NADTyrA_a	TyrA homolog is AGN-specific and NAD⁺-specific
_NADPtyrA_a	_NADPTyrA_a	TyrA homolog is AGN-specific and NADP⁺-specific
_NAD(P)tyrA_a	_NAD(P)TyrA_a	TyrA homolog is AGN-specific but utilizes either NAD⁺ or NADP⁺
_xtyrA_x	_xTyrA_x	Specificity for both the cyclohexadienyl and pyridine nucleotide substrates is unknown

^aAbbreviations in the upper-table box indicate the specificities for the cyclohexadienyl substrate. Abbreviations in the lower-table box indicate specificities for both cyclohexadienyl (right subscripts) and pyridine nucleotide substrates (left subscripts). Combinations not shown can be deduced from the examples given, e.g., a TyrA homolog specific for prephenate and NAD⁺ would be designated _NADTyrA_p.

^bThe abbreviations CDH, PDH, and ADH (shown parenthetically) have been used frequently in the literature.

L O S A L A M O S N A T I O N A L L A B O R A T O R Y • Est 1943
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